Are there genetic predispositions for the development of these diseases?
In 2012 INFANT relaunched a study to determine which are the genes and foods that could prevent two diseases that affect a significant percentage of premature infants who require ventilator and supplemental oxygen.
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that occurs in premature infants and is associated with the immaturity of their lungs, and with the use of ventilator and supplemental oxygen., This problem affects a 25 – 40% of premature infants born weighing less than 1250 gr.
Retinopathy of prematurity (ROP) occurs when blood vessels in the retina grow abnormally due to exposure to high levels of oxygen and can cause blindness or low vision. In the U.S. about 15% of patients who are born weighing less than 1000 g are blind.
However, the reasons why some prematures develop BPD and / or ROP and some not, are not fully elucidated. The study tries to determine the genetic predisposition in the development of these diseases in preterm and also to investigate whether or not the mother’s diet during pregnancy can help avoid these pathologies.
Understanding the role of genes in the development of these diseases can lead to immediate identification of patients “hipersuceptibles” and, on that basis, develop new preventive and therapeutic strategies.
Learning more about the interaction between genes and medical interventions could be extended to other populations, with other diseases (cancer, asthma, etc.) and help resolve them.
In order to carry out this project INFANT is supported by the Institute of Health and Environment (NIEHS), and will be held at the Hospital Italiano, Sanatorio Otamendi, Instituto Médico de Obstetricia (IMO), Sanatorio de la Trinidad de Palermo, Clínica y Maternidad Suizo Argentina y Sanatorio de los Arcos.